IVDB provides pre-computed polymorphisms in IV genes and proteins, which are
grouped by host, subtype and segment. Users are able to search sequence
polymorphisms by host, subtype, and segment. The pre-made alignments,
phylogenetic trees, and geographical distributions in a world map are also
available for instant access.
For Nucleotide Sequence
There are two ways to illustrate the sequence polymorphisms. One is the SNP
distribution plot and the minor allele distribution plot on each
polymorphism site. The other is the consensus sequence with a list of A, T,
C, G statistics on each position.
SNP is defined as the position which has different nucleoside between
sequences. The major allele on SNP position is defined as the nucleoside
whose number on position i is the most, the other nucleosides on this
position are defined as minor allele. For example, if there are 260 As, 5 Ts
and 1 C on position i, the major allele is A, the minor alleles are T and C.
For Protein Sequence
The distribution of each amino acid on each polymorphic site is shown in
tabular list.
Further Analysis
For sequences you have chosen for polymorphism analysis, we offer tools for
further research.
- Download the alignment result file.
- Get the corresponding protein polymorphisms from nucleotide sequences, and vice versa.
- Build phylogenetic tree for these sequences.
- Draw the data distribution map by using our IV Sequence Distribution Tool.
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